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What are the applications of CPG series magnetic stirring batching tanks in the pharmaceutical indus
source：www.sjbyj.com Release time：2026-10-09
The CPG series magnetic stirring and batching tank adopts a magnetic drive structure, eliminating traditional mechanical shaft seals. The tank body can achieve fully enclosed working conditions, and the parts in contact with materials are mostly made of 316L sanitary grade stainless steel. The inner wall is polished and supports CIP in-situ cleaning and SIP steam sterilization. The overall design can meet the relevant GMP standards for pharmaceutical production. It is widely used in various processes such as drug preparation, sterile batching, and buffer solution preparation in the pharmaceutical field. The specific application scenarios are as follows:
1. Concentrated and diluted dispensing of water needles and large infusion solutions
Used for the dissolution, mixing, and volume control of raw materials and excipients in the injection production process. A sealed structure can reduce the invasion of external particles and microorganisms, and lower the risk of drug contamination; The jacket structure supports heating and dissolution, cooling and insulation, and is combined with a stirring system to fully disperse and mix the raw materials and excipients. The ingredients can be prepared under normal pressure and slight negative pressure environment, reducing the evaporation of the medicine and ensuring the uniformity and stability of the medicine components between batches.
2. Preparation of oral liquid and syrup preparations
Ingredients, auxiliary materials, color and aroma adjustment for the extraction of traditional Chinese medicine oral liquids, syrups, and mixtures. The equipment can be sterilized as a whole due to the easy growth of microorganisms in sugar containing systems; The magnetic shaftless structure avoids shaft seal leakage and lubricant mixing into the drug solution, ensuring the hygiene of the formulation. The stirring speed can be adjusted to adapt to the mixing of different viscosity extracts and sugar liquids, reducing local settling.
3. Preparation of sterile preparations and biopharmaceutical buffer solutions
Preparation of sterile raw materials, biologics, cell culture media, dialysis buffer, and purification reagents. The sealed tank body is equipped with a sterile respirator to maintain a clean environment inside the tank. It can complete powder feeding, dissolution, and mixing under sterile conditions, and is suitable for biopharmaceutical sections with high requirements for controlling miscellaneous bacteria, reducing the risk of cross contamination.
4. Ingredients of ointment, gel and external liquid preparation
Dispersion, emulsification and premixing of raw materials of solutions for external use in dermatology, cleaning solutions and gel matrices. For some corrosive pharmaceutical excipients, the equipment material has good corrosion resistance; Fully enclosed mixing can prevent volatile excipients from escaping and reduce external dust from entering the tank. After completing the matrix mixing, it is transported to the next process.
5. Preparation of intermediate systems for raw material drug synthesis
The intermediate reactions, material blending, and extraction and liquid preparation in the production process of chemically synthesized drugs can be stirred and reacted in a closed, slightly positive pressure, or vacuum environment, and some of the treated drugs have volatile components. Magnetic transmission has no leakage, which can reduce the risk of harmful media leakage; The jacket heat exchange facilitates the control of reaction temperature and ensures the stability of the reaction process.
6. Ingredients after preparation and concentration of traditional Chinese medicine extract
Dilute the extracted and concentrated extract of traditional Chinese medicine, mix the excipients, and adjust the pH. The tank is smooth without dead corners, easy to clean, reduces residual materials from previous batches, and lowers the probability of cross contamination between different batches of traditional Chinese medicine extracts; Can be equipped with online pH and temperature detection probes to monitor drug indicators in real time.
1. Concentrated and diluted dispensing of water needles and large infusion solutions
Used for the dissolution, mixing, and volume control of raw materials and excipients in the injection production process. A sealed structure can reduce the invasion of external particles and microorganisms, and lower the risk of drug contamination; The jacket structure supports heating and dissolution, cooling and insulation, and is combined with a stirring system to fully disperse and mix the raw materials and excipients. The ingredients can be prepared under normal pressure and slight negative pressure environment, reducing the evaporation of the medicine and ensuring the uniformity and stability of the medicine components between batches.
2. Preparation of oral liquid and syrup preparations
Ingredients, auxiliary materials, color and aroma adjustment for the extraction of traditional Chinese medicine oral liquids, syrups, and mixtures. The equipment can be sterilized as a whole due to the easy growth of microorganisms in sugar containing systems; The magnetic shaftless structure avoids shaft seal leakage and lubricant mixing into the drug solution, ensuring the hygiene of the formulation. The stirring speed can be adjusted to adapt to the mixing of different viscosity extracts and sugar liquids, reducing local settling.
3. Preparation of sterile preparations and biopharmaceutical buffer solutions
Preparation of sterile raw materials, biologics, cell culture media, dialysis buffer, and purification reagents. The sealed tank body is equipped with a sterile respirator to maintain a clean environment inside the tank. It can complete powder feeding, dissolution, and mixing under sterile conditions, and is suitable for biopharmaceutical sections with high requirements for controlling miscellaneous bacteria, reducing the risk of cross contamination.
4. Ingredients of ointment, gel and external liquid preparation
Dispersion, emulsification and premixing of raw materials of solutions for external use in dermatology, cleaning solutions and gel matrices. For some corrosive pharmaceutical excipients, the equipment material has good corrosion resistance; Fully enclosed mixing can prevent volatile excipients from escaping and reduce external dust from entering the tank. After completing the matrix mixing, it is transported to the next process.
5. Preparation of intermediate systems for raw material drug synthesis
The intermediate reactions, material blending, and extraction and liquid preparation in the production process of chemically synthesized drugs can be stirred and reacted in a closed, slightly positive pressure, or vacuum environment, and some of the treated drugs have volatile components. Magnetic transmission has no leakage, which can reduce the risk of harmful media leakage; The jacket heat exchange facilitates the control of reaction temperature and ensures the stability of the reaction process.
6. Ingredients after preparation and concentration of traditional Chinese medicine extract
Dilute the extracted and concentrated extract of traditional Chinese medicine, mix the excipients, and adjust the pH. The tank is smooth without dead corners, easy to clean, reduces residual materials from previous batches, and lowers the probability of cross contamination between different batches of traditional Chinese medicine extracts; Can be equipped with online pH and temperature detection probes to monitor drug indicators in real time.
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